Clinical Trials

There have been several Randomised Controlled Trials (RCT) on the active ingredient contained in The Weight Loss Gummy (glucomannan). Randomised Controlled Trials (RCT) are considered the “gold standard” of scientific experimentation in humans and below features the most notable RCT studies.

The European Food Safety Authority

The European Food Safety Authority (EFSA) published in the EFSA Journal 2010;8(10):1798 scientific substantiation for the claim of the active ingredient in The Weight Loss Gummy “glucomannan contributes to weight loss”.

Scientific Substantiation

A total of 45 references were cited for the scientific substantiation of the claimed effect: “Reduction of Body Weight (ID 854, 1556, 3725)”.  Among them, 6 reported on intervention studies in humans investigating the effects of glucomannan on body weight. View full report of studies here.

Average Weight Loss: 2.5kg in 56 Days (No Diet or Exercise)

Clinical trial subjects were given the same dose of key active ingredient contained in a serving of The Weight Loss Gummy (1g of glucomannan) 3 times a day before meals with 1-2 glasses of water and lost an average of 2.5kg (5.5lbs) in 56 days without any diet or lifestyle change. View full study here.

50-63% Reduction in Fat Mass in 56 Days

Clinical trial subjects were given the same dose of key active ingredient contained in a daily serving of The Weight Loss Gummy (3g of glucomannan) with diet and exercise. After 56 days, women achieved a 63% reduction in fat mass and waist circumference and 50% for men. View full study here.

Weight Loss: 3.8kg - 4.4kg in 35 Days

Clinical trial subjects lost 3.8kg – 4.4kg in 35 days taking 1.24g of glucomannan on a daily meal plan of 1,200 calories. View full study here.

25% Reduction in Body Weight in 90 Days

Clinical trial subjects were given 4g of glucomannan per day for 90 days on a daily meal plan (1,000kcal: women, 1,300kcal: men) and report a 25% reduction in body weight. View full study here.

Significant Body Weight Loss in 60 Days

Female subjects were given the same dose of key active ingredient contained in a serving of The Weight Loss Gummy (1g of glucomannan) on a daily meal plan of 1,200 calories and within 60 days, achieved statistically significant body weight loss. View full study here.

Significant Fat Loss in 60 Days

Overweight adults were given the same dose of key active ingredient contained in a daily serving of The Weight Loss Gummy (3g of glucomannan) and within 60 days achieved statistically significant reductions in scale weight, percentage body fat, fat mass, total cholesterol, and low-density lipoprotein (LDL) cholesterol, without loss of lean mass and bone density often associated with weight loss. View full study here.

Long-Term Treatment of Severe Obesity

Severely obese patients consumed 4g of glucomannan daily for 57 days on a calorie reduced diet and found effective results for the long-term treatment of severe obesity. View full study here.

Reduced Appetite and Food Intake

Ghrelin is the hunger hormone produced in the gut, triggering the brain to promote eating. Clinical trial subjects with type 2 diabetes consumed glucomannan for 28 days and report a reduction in ghrelin activity, reduced appetite and food intake. View full study here.

Reduction in BMI and Waist Circumference in 28 Days

Clinical trial subjects (postmenopausal women with abdominal obesity) consumed 100ml of aronia juice enriched with glucomannan over 28 days without any change in diet or lifestyle. Results observe a reduction in BMI and waist circumference and an improvement in blood lipid levels, decrease in blood pressure and increase in activity of antioxidant enzymes. View full study here.

Contributes to Weight Loss in Childhood Obesity

Clinical trial subjects (obese children) consumed 2-3g of glucomannan per day with a balanced diet for 4 months. Excess weight, cholesterol and blood lipid levels decreased significantly with findings that glucomannan can be used to treat obesity and dyslipidemia in children. View full study here.

Promotes Excretion of Fats and Reduction in Cholesterol

Clinical trial subjects with type 2 diabetes consumed 3.6g of glucomannan per day for 28 days and report a reduction in cholesterol levels and stimulated excretion of fats. View full study here.

Reduction in Body Weight and Cholesterol (14 Studies)

14 studies showed glucomannan had a beneficial affect on total cholesterol, LDL cholesterol, triglycerides, body weight, and fasting blood glucose. View full study here.

Treatment for Constipation

Clinical trial subjects (with constipation) showed a statistically significant improvement in transit time with a return to within the normal ranges after treatment with glucomannan. View study here and here.